J Dent Res Dent Clin Dent Prospects. 2015;9(1):1-5.
doi: 10.5681/joddd.2014.001
PMID: 25024832
PMCID: PMC4091693
  Abstract View: 195
  PDF Download: 326

Original Research

The Effect of Different Concentrations of Chlorhexidine Gluconate on the Compressive Strength of Mineral Trioxide Aggregate

Maryam Bidar 1, Neda Eslami 2 * , Neda Naghavi 3, Zohreh Fasih 4, Negin Attaran Mashhadi 5

1 Professor of Endodontics, Dental Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
2 Assistant Professor of Orthodontics, Dental Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
3 Assistant Professor of Endodontics, Dental Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
4 Dentist, Private Practice, Mashhad, Iran
5 Student of Medicine, Member of Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Article

Background and aims. Substituting chlorhexidine (CHX) for water has been shown to enhance antimicrobial activity of mineral trioxide aggregate (MTA). The purpose of this study was to compare the compressive strength of MTA mixed with distilled water, 0.12% and 0.2% chlorhexidine. Materials and methods. MTA was mixed according to manufacturer’s instructions in group I (n = 20). In groups II & III, 0.12% and 0.2% CHX liquid was substituted for water, respectively. Samples were condensed with moderate force into 20 tubes with 1.5 × 5 mm dimensions and were allowed to set for 72 hours at 37°C in 100% humidity. After being removed from the molds, their compressive strength was determined using Instron testing machine. Each group was divided into two subgroups according to the time of testing (at 72 hours, and one week). Fractured surfaces of 4 specimens in each group were then evaluated under Scanning Electron Microscope (SEM) to determine their microstructure. One-way ANOVA, Tukey, and paired sample t-test was used for statistical analysis. P < 0.05 was set as significant. Results. There was no significant difference between three groups in terms of their compressive strength after 72 hours. However, the compressive strength of group II was significantly higher than group I (P = 0.034) and group III (P = 0.021) after one week. Crystalline microstructure was similar in all groups. Conclusion. Substitution of 0.012% chlorhexidine for water significantly increased the compressive strength of MTA at 1 week without significant change in crystalline structure.
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Submitted: 15 Mar 2015
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