Tabriz University of Medical Sciences Journal of Dental Research, Dental Clinics, Dental Prospects 2008-210X 6 4 2012 11 12 Management of Physiological Hyperpigmentation of Oral Mucosa by Cryosurgical Treatment: A Case Report 148 151 10.5681/joddd.2012.030 EN Maryam Talebi Niloofar Farmanbar Salman Abolfazli Alireza Sarraf Shirazi Journal Article 10.5681/joddd.2012.030 2012 02 02 Melanin hyperpigmentation is the result of melanin granules. "Black gums" may cause esthetic problems. Different treatment modalities have been used with the aim of removing pigmentations for esthetic reasons, all of which have some advantages and disadvantages. Recurrent lesions are the most important concept in all of these treatments. Cryotherapy is a method of tissue destruction by rapid freezing. It is an atraumatic, costeffective and simple method for treating oral pigmentation. This report presents the effects of cryotherapy on physiologic pigmentations of oral mucosa in a 9-year-old boy. In this case no recurrent lesions were observed after 12 months.