Tabriz University of Medical Sciences Journal of Dental Research, Dental Clinics, Dental Prospects 2008-210X 17 1 2023 04 03 Effect of LED photobiomodulation on dental implant osseointegration: An in vivo study 28 34 10.34172/joddd.2023.36954 EN Jean-Marc Foletti https://orcid.org/0000-0002-2471-859X Floriane Remy Luc Chevenement Manon Sterba https://orcid.org/0000-0001-5360-6784 Patrick Tavitian Laurent Badih Olivia Kenck-Veran Journal Article 10.34172/joddd.2023.36954 2022 12 27 2023 01 25 Background. Photobiomodulation (PBM) may be prescribed after dental surgery to accelerate tissue healing and improve implant stability. The objective of this study is to evaluate the efficiency of LED-PBM on the dental implant osseointegration. Methods. A total of 48 implants (KontactTM) were inserted in 8 Yucatan minipigs (6 implants per minipig) divided into 2 groups (test and control). The test group received LED-PBM with a total energy of 124.2 J/cm2 delivered over 4 sessions (at day0, day+8, day+15 and day+28) lasting 12 minutes each. At day+28, all animals were sacrificed, and their mandibles removed to perform histologic and histomorphometric analysis. Implant osseointegration was evaluated using the computation of bone/implant contact (BIC) index and bone surface/total surface (BS/ TS) ratio. The groups were compared using Student’s unpaired t test. Results. BIC index and BS/TS ratio were significantly higher within the test group as compared to the control group (P<0.01). Histologic observations on bone tissues demonstrated that LED-PBM may improve and accelerate dental implant osseointegration: 25% of dental implants analyzed within the test group were completely osseointegrated, versus 12.5% within the control group. Conclusion. This experimental study indicates that LED-PBM contributes to enhancing implant treatment outcomes.