Tabriz University of Medical Sciences Journal of Dental Research, Dental Clinics, Dental Prospects 2008-210X 18 3 2024 09 07 Exploring the potential of tomato juice (Solanum lycopersicum L.) patch for tooth bleaching 157 164 10.34172/joddd.41042 EN Laifa Annisa Hendarmin https://orcid.org/0000-0001-5281-395X Berliana Novianita https://orcid.org/0009-0005-1006-1688 Yuni Anggraeni https://orcid.org/0000-0001-8618-1372 Khairunissa Febriyanti https://orcid.org/0009-0009-5667-8033 Journal Article 10.34172/joddd.41042 2024 01 28 2024 08 10 Background. Tomato, renowned for its tooth-whitening properties due to its hydrogen peroxide and peroxidase enzyme content, requires formulation for enhanced applicability. This study assessed the dental whitening efficacy of a patch containing tomato juice as the active ingredient. Methods. Tomato juice patches were formulated at concentrations of 55%, 60%, and 65%. A control group (C) containing a 12% hydrogen peroxide patch was also included. A matrix layer of the patches was prepared using the solvent casting method at 40 for 18 h, with Tegaderm™ applied as the backing layer. For the dental whitening procedure, each group of patches was applied to the labial surface of anterior stained teeth (n=6/group) for 3 h, repeated 14 times. Tooth brightness was evaluated qualitatively and quantitatively using digital dental photo CIEL*a*b* analysis. Meanwhile, enamel surfaces were examined under a scanning electron microscope (SEM). Repeated-measures analysis of variance (ANOVA) was employed for statistical analysis. Results. The application of tomato juice patches led to enhanced tooth brightness. The patch containing 65% tomato juice significantly improved stained tooth brightness (P<0.05). SEM analysis revealed less enamel erosion with the 65% tomato juice patch compared to the 12% hydrogen peroxide patch. Conclusion. Tomato juice patches effectively increased tooth brightness while minimizing demineralization. Further research is needed to optimize formulation and explore its potential.