J Dent Res Dent Clin Dent Prospects. 2018;12(3):201-207.
doi: 10.15171/joddd.2018.031
PMID: 30443306
PMCID: PMC6231146
  Abstract View: 288
  PDF Download: 333
  Full Text View: 204

Original Article

Effect of pH on solubility of white Mineral Trioxide Aggregate and Biodentine: An in vitro study

S Pushpa 1 * , Chakit Maheshwari 1, Garima Maheshwari 1, N Sridevi 1, Puneeta Duggal 1, Puneet Ahuja 1

1 Department of Conservative Dentistry and Endodontics, Rama Dental College-Hospital and Research Centre, Kanpur - 208024, Uttar Pradesh, India


Background. The aim of this study was to evaluate the effect of acidic, neutral and alkaline environments on the solubility of white mineral trioxide aggregate (WMTA) and Biodentine (BD).

Methods. Thirty-nine ring molds were randomly divided into three groups of A, B, and C (n = 12) with pH values of 7.4, 4.4 and 10.4, respectively, and an empty mold was used as a control. Each group was further divided into two subgroups (1 and 2) according to the material studied. The samples in groups A, B and C were transferred into synthetic tissue fluid buffered at pH values of 7.4, 4.4 and 10.4, respectively, and kept in an incubator at 37°C with 100% humidity. Daily solubility at 1-, 2-, 5-, 14-, 21-, and 30-day intervals and cumulative solubility up to 5-, 14-, and 30-day intervals were calculated. Statistical analysis was carried out with independent-samples t-test, two-way ANOVA and post hoc Tukey tests using SPSS 18. Statistical significance was set at P<0.05.

Results. Both WMTA and BD exhibited the highest solubility in acidic pH with 5.4235±0.1834 and 10.7516±0.0639 mean cumulative solubility values at 30-day interval, respectively. At all exposure times, BD was significantly more soluble than WMTA (P<0.001).

Conclusion. Acidic periapical environment jeopardized the solubility of both WMTA and BD, affecting their sealing characteristics in clinical applications like perforation repair procedures and blunderbuss canals.

First name
Last name
Email address
Security code

Article Viewed: 288

Your browser does not support the canvas element.

PDF Downloaded: 333

Your browser does not support the canvas element.

Full Text Viewed: 204

Your browser does not support the canvas element.

Submitted: 31 May 2017
Accepted: 16 Aug 2018
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - FireFox Plugin)