J Dent Res Dent Clin Dent Prospects. 2020;14(3): 191-197.
doi: 10.34172/joddd.2020.030
  Abstract View: 131
  PDF Download: 87

Clinical Dentistry

Original Article

Clinical and microbiological effects of adjunctive photodynamic diode laser therapy in the treatment of chronic periodontitis: A randomized clinical trial

Sahana Mallineni 1 ORCID logo, Sreenivas Nagarakanti 1* ORCID logo, Sumanth Gunupati 1 ORCID logo, Ramesh Reddy BV 1, Mahaboob V Shaik 2, Vijay K Chava 1

1 Department of Periodontology, Narayana Dental College & Hospital, Nellore, India
2 Department of Genetics, Advanced Research Centre, Narayana Medical College & Hospital, Nellore, India
*Corresponding authors: Sreenivas Nagarakanti. Email: sreenivasnagarakanti@gmail.com


Background. Conventional mechanical debridement alone cannot eliminate bacteria and their products from periodontal pockets. Adjunctive therapies improve tissue healing through detoxification and bactericidal effects. Photodynamic therapy (PDT) is a non-invasive treatment procedure that involves the use of a dye as a photosensitizer to attach to the target cell and be activated by a photon of an appropriate wavelength. This study aimed to assess the effectiveness of PDT in treating periodontitis as an adjunct to scaling and root planing.

Methods. Fifteen subjects with chronic periodontitis were treated randomly with scaling and root planing (SRP), followed by a single PDT (test) or SRP (control) episode alone. Full-mouth plaque index (PI), sulcus bleeding index (SBI), probing depth (PD), and clinical attachment level (CAL) were assessed at baseline and 1-month and 3-month intervals. Microbiological evaluation of Porphyromonas gingivalis (Pg) in subgingival plaque samples was performed using a commercially available real-time polymerase chain reaction.

Results. The results revealed a significant difference in PI, SBI, PD, CAL, and microbiological parameters between the groups one and three months after treatment.

Conclusion. A combination of PDT and SRP gave rise to a significant improvement in clinical and microbiological parameters in patients with chronic periodontitis.

Keywords: Chronic periodontitis, Photodynamic therapy, Hotosensitizing agents, Polymerase chain reaction, Porphyromonas gingivalis
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Submitted: 31 Dec 2019
Revision: 04 Feb 2020
Accepted: 08 Feb 2020
ePublished: 21 Sep 2020
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