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J Dent Res Dent Clin Dent Prospects. 2023;17(1): 28-34.
doi: 10.34172/joddd.2023.36954
PMID: 37650019
PMCID: PMC10462914
  Abstract View: 881
  PDF Download: 367
  Full Text View: 146

Basic Research

Original Article

Effect of LED photobiomodulation on dental implant osseointegration: An in vivo study

Jean-Marc Foletti 1,2* ORCID logo, Floriane Remy 2, Luc Chevenement 2, Manon Sterba 3 ORCID logo, Patrick Tavitian 4, Laurent Badih 3, Olivia Kenck-Veran 5

1 Department of Oral and maxillofacial Surgery, APHM, Conception University Hospital, Marseille, France
2 Aix-Marseille Univ, Gustave Eiffel Univ, LBA, Marseille, France
3 Glad Medical SAS, Salon-de-Provence, France
4 Department of Dentistry, APHM, la Timone University Hospital, Marseille, France
5 Dental Private Practice, Selestat, France
*Corresponding Author: Corresponding author: Jean Marc Foletti, Email: , Email: jeanmarc.foletti@ap-hm.fr

Abstract

Background. Photobiomodulation (PBM) may be prescribed after dental surgery to accelerate tissue healing and improve implant stability. The objective of this study is to evaluate the efficiency of LED-PBM on the dental implant osseointegration.

Methods. A total of 48 implants (KontactTM) were inserted in 8 Yucatan minipigs (6 implants per minipig) divided into 2 groups (test and control). The test group received LED-PBM with a total energy of 124.2 J/cm2 delivered over 4 sessions (at day0, day+8, day+15 and day+28) lasting 12 minutes each. At day+28, all animals were sacrificed, and their mandibles removed to perform histologic and histomorphometric analysis. Implant osseointegration was evaluated using the computation of bone/implant contact (BIC) index and bone surface/total surface (BS/ TS) ratio. The groups were compared using Student’s unpaired t test.

Results. BIC index and BS/TS ratio were significantly higher within the test group as compared to the control group (P<0.01). Histologic observations on bone tissues demonstrated that LED-PBM may improve and accelerate dental implant osseointegration: 25% of dental implants analyzed within the test group were completely osseointegrated, versus 12.5% within the control group.

Conclusion. This experimental study indicates that LED-PBM contributes to enhancing implant treatment outcomes.

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Submitted: 27 Dec 2022
Accepted: 25 Jan 2023
ePublished: 03 Apr 2023
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