Logo-joddd
J Dent Res Dent Clin Dent Prospects. 2023;17(1): 47-53.
doi: 10.34172/joddd.2023.37014
PMID: 37650014
PMCID: PMC10462918
  Abstract View: 843
  PDF Download: 344
  Full Text View: 98

Clinical Dentistry

Original Article

Comparison of the anesthetic effect of alkalized lidocaine versus non-alkalized lidocaine administered at a slow rate in mandibular primary molars

Karen Torres-Rojas 1 ORCID logo, Victor Chumpitaz-Cerrate 2,3 ORCID logo, Lesly Chávez-Rimache 2* ORCID logo, Daniella Núñez-Díaz 1 ORCID logo, Vanessa Pérez-Jimenez 2 ORCID logo

1 Department of Dentistry, Universidad Nacional Mayor de San Marcos, Lima, Peru
2 Group Investigación en Ciencias Básicas Estomatológicas (ICBEST), Universidad Nacional Mayor de San Marcos, Lima, Peru
3 Pharmacology Laboratory, Universidad Científica del Sur, Lima, Peru
*Corresponding Author: Corresponding author: Chávez-Rimache Lesly, Email: , Email: leslykcr0410@gmail.com

Abstract

Background. There are several invasive dental procedures that require local anesthetics. However, its infiltration is usually associated with anxiety and fear, increasing the perception of pain in pediatric patients. For this reason, it is important to evaluate different strategies for its application. We compared the anesthetic effect of the administration of 2% lidocaine with epinephrine 1:80000 non-alkalized at slow speed and alkalized at fast speed to block the inferior alveolar nerve in deciduous molars.

Methods. A crossover clinical trial was carried out whose sample consisted of 38 patients between 6-10 years who required bilateral pulp treatment in their first mandibular primary molars. At the first appointment, they received 2% lidocaine with 1:80000 alkalinized epinephrine administered at a fast rate, and at the second appointment, 2% lidocaine with 1:80000 non-alkalized epinephrine administered at a low speed. We evaluated the onset of action, duration of the anesthetic effect, and intensity of pain during its infiltration.

Results. We found that non-alkalized lidocaine at slow speed had a shorter onset time of action (57.21±22.21 seconds) and longer duration of effect (170.82±43.75 minutes) compared to administration of alkalinized lidocaine at fast speed (74.03±22.09 seconds, 148.24±36.24 minutes, respectively). There was no difference in the level of pain intensity.

Conclusion. In this study, the slow administration of the non-alkalized local anesthetic showed a shorter onset time of action and a longer duration of the anesthetic effect in comparison with the alkalized local anesthetic administered at a rapid rate in the blockade of the inferior alveolar nerve in deciduous molars.

First Name
Last Name
Email Address
Comments
Security code


Abstract View: 844

Your browser does not support the canvas element.


PDF Download: 344

Your browser does not support the canvas element.


Full Text View: 98

Your browser does not support the canvas element.

Submitted: 19 Nov 2022
Accepted: 09 Jan 2023
ePublished: 03 Apr 2023
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)