Abstract
            Background. Tomato, renowned for its tooth-whitening properties due to its hydrogen peroxide  and peroxidase enzyme content, requires formulation for enhanced applicability. This study  assessed the dental whitening efficacy of a patch containing tomato juice as the active ingredient.  
  Methods. Tomato juice patches were formulated at concentrations of 55%, 60%, and 65%. A  control group (C) containing a 12% hydrogen peroxide patch was also included. A matrix layer  of the patches was prepared using the solvent casting method at 40 for 18 h, with Tegaderm™  applied as the backing layer. For the dental whitening procedure, each group of patches was  applied to the labial surface of anterior stained teeth (n=6/group) for 3 h, repeated 14 times. Tooth  brightness was evaluated qualitatively and quantitatively using digital dental photo CIEL*a*b*  analysis. Meanwhile, enamel surfaces were examined under a scanning electron microscope  (SEM). Repeated-measures analysis of variance (ANOVA) was employed for statistical analysis.  
  Results. The application of tomato juice patches led to enhanced tooth brightness. The patch  containing 65% tomato juice significantly improved stained tooth brightness (P<0.05). SEM  analysis revealed less enamel erosion with the 65% tomato juice patch compared to the 12%  hydrogen peroxide patch.  
  Conclusion. Tomato juice patches effectively increased tooth brightness while minimizing  demineralization. Further research is needed to optimize formulation and explore its potential.