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J Dent Res Dent Clin Dent Prospects. 2015;9(4): 267-273. doi: 10.15171/joddd.2015.047
PMID: 26889365        PMCID: PMC4753037

Original Research

Garlic (Allium sativum) Fresh Juice Induces Apoptosis in Human Oral Squamous Cell Carcinoma: The Involvement of Caspase-3, Bax and Bcl-2

Farrokh Farhadi 1, Salar Jahanpour 2, Kameliya Hazem 3 * , Amirala Aghbali 4, Behzad Baradran 5, Seyyed Mahdi Vahid Pakdel 6

Cited by CrossRef: 9

1- Țigu A, Moldovan C, Toma V, Farcaș A, Moț A, Jurj A, Fischer-Fodor E, Mircea C, Pârvu M. Phytochemical Analysis and In Vitro Effects of Allium fistulosum L. and Allium sativum L. Extracts on Human Normal and Tumor Cell Lines: A Comparative Study. Molecules. 2021;26(3):574 [Crossref]
2- Chugh N, Desai V, Sharma R, Chandwani P. Allium sativum. 2023;10(1):8 [Crossref]
3- Martínez-Pascual M, Sacristán S, Toledano-Macías E, Hernández-Bule M. Electric Stimulation at 448 kHz Modulates Proliferation and Differentiation of Follicle Dermal Papilla Cells. Cosmetics. 2024;11(6):187 [Crossref]
4- Bina F, Soleymani S, Toliat T, Hajimahmoodi M, Tabarrai M, Abdollahi M, Rahimi R. Plant-derived medicines for treatment of endometriosis: A comprehensive review of molecular mechanisms. Pharmacological Research. 2019;139:76 [Crossref]
5- Pérez-Durán J, Luna A, Portilla A, Martínez P, Ceballos G, Ortíz-Flores M, Solis-Paredes J, Nájera N. (−)-Epicatechin Inhibits Metastatic-Associated Proliferation, Migration, and Invasion of Murine Breast Cancer Cells In Vitro. Molecules. 2023;28(17):6229 [Crossref]
6- Della Corte L, Noventa M, Ciebiera M, Magliarditi M, Sleiman Z, Karaman E, Catena U, Salvaggio C, Falzone G, Garzon S. Phytotherapy in endometriosis: an up-to-date review. 2020;17(3) [Crossref]
7- Almatroodi S, Alsahli M, Almatroudi A, Rahmani A. Garlic and its Active Compounds: A Potential Candidate in The Prevention of Cancer by Modulating Various Cell Signalling Pathways. ACAMC. 2019;19(11):1314 [Crossref]
8- Siddiqui Z, Khan M, Badruddeen B, Akhtar J, Ahmed M. In Vitro Antioxidant Activity, Pharmacognostical Evaluation, HPTLC and FTIR Fingerprinting of Phyllanthus Acidus L. Stem Bark Extract for Better Application in Phytotherapy. Biomed Pharmacol J. 2023;16(3):1381 [Crossref]
9- P. V, D. D, Bala M, N. S. Photoactivated [Mn(CO)3Br(μ-bpcpd)]2 induces apoptosis in cancer cells via intrinsic pathway. Journal of Photochemistry and Photobiology B: Biology. 2018;188:28 [Crossref]
10- Ramanathan E, Ponnuchamy K, Muthusamy G, Varatharajan N, Sabapathi D, Selvaraj A. Chitosan-stabilized platinum nanoparticles induce apoptotic cell death in breast cancer cells. Appl Nanosci. 2023;13(6):3867 [Crossref]
11- Hussein J, El-khayat Z, Farouk H. Antitumor Activity of Selenium in Ehrlich Ascites Carcinoma Bearing Mice. Biomed Pharmacol J. 2023;16(3):1353 [Crossref]
12- Bai J, Bai Y, Wang X, Zheng W, Zhang L. Carbon Monoxide-Releasing Molecule-3 Ameliorates Acute Lung Injury in a Model of Hemorrhagic Shock and Resuscitation: Roles of p38MAPK Signaling Pathway. 2021;55(6):816 [Crossref]
13- Yang H, Yu G, Wang Y, Guo X. REST-restrained lncRNA EPB41L4A-AS2 Modulates Laryngeal Squamous Cell Carcinoma Development via Regulating miR-1254/HIPK2 Pathway. CPPS. 2023;24(9):737 [Crossref]
14- Ma L, Shen H, Fang C, Chen T, Wang J. Camellia Seed Cake Extract Supports Hair Growth by Abrogating the Effect of Dihydrotestosterone in Cultured Human Dermal Papilla Cells. Molecules. 2022;27(19):6443 [Crossref]

Featured Prospective Highlight

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