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J Dent Res Dent Clin Dent Prospects. 2016;10(4): 226-233. doi: 10.15171/joddd.2016.036
PMID: 28096948        PMCID: PMC5237669

Original Article

Efficacy of Hypozalix spray and propolis mouthwash for prevention of chemotherapy-induced oral mucositis in leukemic patients: A double-blind randomized clinical trial

Hosein Eslami 1, Firouz Pouralibaba 1, Parisa Falsafi 1, Sepideh Bohluli 1, Babak Najati 2, Ramin Negahdari 3 * , Milad Ghanizadeh 4

Cited by CrossRef: 17

1- Münstedt K, Männle H. Using Bee Products for the Prevention and Treatment of Oral Mucositis Induced by Cancer Treatment. Molecules. 2019;24(17):3023 [Crossref]
2- Raghunand Sindhe J, Asha V, Arvind M, Shabana S, Sowbhagya Lakshmi A, Tanvi K, Ananta G. A Systematic Review of the Efficacy and Safety of Mulberry Formulations for Chemotherapy- and/or Radiotherapy-Induced Oral Mucositis. 2024; [Crossref]
3- Zhang Q, Wang F, Jia K, Kong L. Natural Product Interventions for Chemotherapy and Radiotherapy-Induced Side Effects. Front Pharmacol. 2018;9 [Crossref]
4- AKBAŞ M, AKÇAKAYA A, KARTAL M. Palliative Care and Phytotherapy in Patients with Cancer. Bezmialem Science. 2023;11(1):132 [Crossref]
5- Amiri Khosroshahi R, Talebi S, Zeraattalab-Motlagh S, Imani H, Rashidi A, Travica N, Mohammadi H. Nutritional interventions for the prevention and treatment of cancer therapy-induced oral mucositis: an umbrella review of systematic reviews and meta-analysis. 2023;81(9):1200 [Crossref]
6- Zhang X, Sun D, Qin N, Liu M, Zhang J, Li X. Comparative prevention potential of 10 mouthwashes on intolerable oral mucositis in cancer patients: A Bayesian network analysis. Oral Oncology. 2020;107:104751 [Crossref]
7- Peng T, Tsai F, Wu T, Rai V. Effects of various treatments for preventing oral mucositis in cancer patients: A network meta-analysis. PLoS ONE. 2022;17(12):e0278102 [Crossref]
8- Darbanian N, Nobahar M, Ghorbani R. Effect of propolis mouthwash on the incidence of ventilator-associated pneumonia in intensive care unit patients: a comparative randomized triple-blind clinical trial. BMC Oral Health. 2024;24(1) [Crossref]
9- Sepúlveda C, Núñez O, Torres A, Guzmán L, Wehinger S. Antitumor Activity of Propolis: Recent Advances in Cellular Perspectives, Animal Models and Possible Applications. Food Reviews International. 2020;36(5):429 [Crossref]
10- Yu Y, Deng J, Jin X, Zhang Z, Zhang X, Zhou X. Effects of 9 oral care solutions on the prevention of oral mucositis: a network meta-analysis of randomized controlled trials. 2020;99(16):e19661 [Crossref]
11- Alghutaimel H, Matoug-Elwerfelli M, Alhaji M, Albawardi F, Nagendrababu V, Dummer P. Propolis Use in Dentistry: A Narrative Review of Its Preventive and Therapeutic Applications. International Dental Journal. 2024;74(3):365 [Crossref]
12- Miranda-Silva W, Gomes-Silva W, Zadik Y, Yarom N, Al-Azri A, Hong C, Ariyawardana A, Saunders D, Correa M, Arany P, Bowen J, Cheng K, Tissing W, Bossi P, Elad S. MASCC/ISOO clinical practice guidelines for the management of mucositis: sub-analysis of current interventions for the management of oral mucositis in pediatric cancer patients. Support Care Cancer. 2021;29(7):3539 [Crossref]
13- Kuo C, Wang R, Wang H, Li C. Meta-analysis of randomized controlled trials of the efficacy of propolis mouthwash in cancer therapy-induced oral mucositis. Support Care Cancer. 2018;26(12):4001 [Crossref]
14- Taghadosi M, Akbari H, Ganjoori F, Fakharian M. Effects of the Mouthwash Containing Pomegranate Seed Oil on Improving Oral Mucositis in Patients Undergoing Chemotherapy. J Adv Med Biomed Res. 2022;30(142):423 [Crossref]
15- Bayırlı A, Kıvrak İ, Saruhan E, Cantaş Türkiş F. Comparison of matrix metalloproteinase levels in periodontal pockets treated with chlorhexidine and propolis. 2024;11(4):729 [Crossref]

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